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DeCS
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Descriptor English:
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Complement Membrane Attack Complex
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Descriptor Spanish:
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Complejo de Ataque a Membrana de Complemento
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Descriptor Portuguese:
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Complexo de Ataque à Membrana de Complemento
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Synonyms English:
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Membrane Attack Complex
Complement Complex C5b-9
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Tree Number:
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D12.776.124.486.274.930
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Definition English:
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A product of COMPLEMENT ACTIVATION cascade, regardless of the pathways, that forms transmembrane channels causing disruption of the target CELL MEMBRANE and cell lysis. It is formed by the sequential assembly of terminal complement components (COMPLEMENT C5B; COMPLEMENT C6; COMPLEMENT C7; COMPLEMENT C8; and COMPLEMENT C9) into the target membrane. The resultant C5b-8-poly-C9 is the "membrane attack complex" or MAC. |
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Indexing Annotation English:
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DF: COMPLEMENT MAC
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Pharmacological Action:
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Immunologic Factors
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History Note English:
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90
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Allowable Qualifiers English:
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Record Number:
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24583
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Unique Identifier:
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D015938
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Occurrence in VHL:
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Similar:
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DeCS SciELO LILACS LIS
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